Sente for Mac

From Third Street Software:

Sente is for people who need to keep up with the biomedical research literature. Sente (pronounced SEN-tay) is a simple yet powerful tool for searching Pubmed, organizing the search results and staying current as new information is published. With Sente, you can quickly retrieve and review thousands of references to come up to speed on a new topic, and organize large collections of citations for quick access in your ongoing research.

With Sente you can:
Search Pubmed and download 1,000 citations, including abstracts, in less than a minute;
Flip through a large collection of citations as quickly as you can skim through the citation and abstract - one keystroke is all that it takes to move on to the next citation;
Assign custom keywords to any paper with a single keystroke;
Create dynamic subsets of your data using, for example, your custom keywords, or other information found in each entry;
Annotate any reference with your own notes using the built in rich text editor;
Attach the full text version of an article to its citation in Sente for easy access in the future;
Stay current on all searches as Sente automatically checks for new references every day.