Portable Thunderbird for Mac

From FreeSoftware Mac User Group:

Portable Thunderbird is the popular Mozilla Thunderbird e-mail client packaged so you can carry around with you on any portable device, USB thumb drive, iPod, portable hard drive, memory card, other portable device (also on your internal hard disk) as long as it has 60 MB of free space and use on any Mac OS X computer, taking your email, address book and account settings with you.

1. Drag the "Portable Thunderbird OS X" folder to your portable device, USB thumb drive, iPod, portable hard drive, memory card, other portable device (also to your internal hard disk) as long as it has 60 MB of free space.
2. Clicking "Portable Thunderbird" will open Thunderbird from your portable device, wait a while before Thunderbird start.
3. If a local copy of Thunderbird is running an alert window allow you to quit it.

Using your data
You can copy your local Profile folder to Portable Thunderbird when "Copy local Profile" window ask you. So, if you wish to use your address, mail, preferences you already have on your system, just click "Copy" when prompt, and select the folder "/Users/[username]/Library/Thunderbird/Profiles/********.default/".
Thunderbird application and Profile folder are inside the bundle: Portable Thunderbird.app/Contents/Resources/

Support Forum
Post questions, tips, suggestions, clues, helps, bugs to our Portable Apps OS X support forum