Fatbits

From John Ridges:

Fatbits is a very fast, compact, easy to use and versatile screen magnifier for graphic designers and the visually impaired. It magnifies an area of the screen centered around the mouse pointer and paints the giant pixels into a small, tastefully decorated window, which can be indispensable when you want to see something right down to the last pixel. As an accessibility tool, it can perform text smoothing and can modify the colors it displays to help those with color vision deficiency. Fatbits works well with multiple monitors, optionally paints a grid to help identify individual pixels, and can display color and position information.