A dead-simple commercial-removal application designed for Vista Media Center users. Here is zero configuration required, however, there are plenty of options if that's your thing.
Lifextender is pretty simple. It scans the directory that Media Center records TV to every X minutes for new TV shows. All new TV shows are queued up to be analyzed and scanned for annoying commercials. After a show has been analyzed, a new file is created from the original with commercials cut out. The original show is then replaced by the new, commercial-free show. Rinse and repeat.
Version 0.9.4.6 is compatible with Windows Vista Premium and Windows Vista Ultimate.