MapDraw for Mac

From DNASTAR:

MapDraw offers you six different map formats for viewing your sequence and the restriction sites you choose. You can view linear or circular maps for sequences ranging from a few to millions of nucleotides. Specific sets of sites can be created, saved and applied to any sequence separately or in combination. Clear explanations of ligation and fill possibilities identify potential cloning problems and you can select restriction sites based on their cloning compatibilities to ensure proper site selection for digestions. MapDraw displays translations of any or all six reading frames alongside the restriction sites and lets you create and selectively display features and annotations on your maps. MapDraw even lets you open sequences of multiple file types including those from NCBI's databases via accession number, the integrated BLAST tool, or the Entrez text query tool*.