Automates the design of highly specific synthetic oligos for MLPA assays.
MLPA Designer automates the design of highly specific synthetic oligos for MLPA assays. MLPA (Multiplex Ligation dependent Probe Amplification) is a simple, high throughput multiplex PCR technique introduced by MRC-Holland that allows detection of abnormal copy numbers of up to 50 different genomic DNA or RNA sequences. This easy to perform technique requires the use of a thermocycler and capillary electrophoresis equipment. MLPA Designer strictly adheres to the guidelines laid by MRC-Holland for designing of MLPA oligos.