From Dennis Baggott and Sons:
QUAD Help Desk Client Server Edition was developed for those who prefer to use Microsoft's SQL Server 2005 as the backend database. The front end will be familiar to those who have used QUAD HD Standard or Pro Edition. This new edition can also be used with Microsoft's Express Edition of Microsoft SQL Server 2005. The download includes two setup files--one with user logins and procedure security, the other without logins.