Used MultiGeneBlast for Windows?


Editors’ Review

Download.com staff
This open source tool identifies homologous gene clusters by combining multiple BlastP results. It sorts genomic regions by hits, synteny conservation, and cumulative score, aiding synthetic biology projects and operon library creation.
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MultiGeneBlast 0/1
  • Pros

    • Identifies homologous multi-gene modules like operons.
    • Sorts regions by hits, synteny conservation, and cumulative score.
    • Performs architecture searches for user-specified amino acid combinations.
    • Tracks source nucleotide and coordinates from protein entries.
    • Aids creation of synthetic operon libraries for research.
  • Cons

    • No graphical user interface is described.
    • Dependent on specific NCBI GenBank protein entry format.
    • Lacks native tools for results visualization.
    • Relies on combining results from individual BlastP runs.
    • Does not describe support for other database formats.

Used MultiGeneBlast for Windows?


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Full Specifications

GENERAL
Release
Latest update
Version
1.1.5
OPERATING SYSTEMS
Platform
Windows
Operating System
  • Windows 7
  • Windows Vista
  • Windows 2003
  • Windows XP
  • Windows 10
Additional Requirements
None
POPULARITY
Total Downloads
101
Downloads Last Week
1

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Developer’s Description

Identify homolog of multi-gene modules such as operons and gene clusters.
MultiGeneBlast is an open source tool based on a reformatting of the FASTA headers of NCBI GenBank protein entries, using which it can track down their source nucleotide and coordinates. MultiGeneBlast can aid in the detection of such multigene parts for synthetic biology projects. A synthetic library of operons can be created based on its output to identify those operons whose function is closest to the one desired by the user. This tool provides the opportunities to identify all homologous genomic regions by combining the results of single BlastP runs on each gene, and sorting genomic regions from any GenBank entry by the number of hits, synteny conservation, and cumulative Blast bit score. Architecture searches can be performed to find any genomic regions with Blast hits to any user-specified combination of amino acid sequences.

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