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4Peaks Analysis
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Not written by CNET Staff.
4Peaks is a free chromatogram viewing program designed specifically for molecular biologists to visualize and edit DNA trace files. This software offers a minimalist interface while packing a variety of features that facilitate the viewing, analysis, and editing of DNA sequences. It supports several sequence trace file formats, such as SCF, ZTR, EXP, BIO, and CTF, and includes options for protein and DNA analysis through plug-ins. Users can quickly highlight specific motifs using a basic search tool, and the program's integration with multiple translation dictionaries enhances the visualization of mutation effects.
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In addition to viewing capabilities, 4Peaks includes a Basic Local Alignment Search Tool (BLAST) that allows users to compare their DNA sequences with those in the National Center for Biotechnology Information (NCBI) database. This functionality simplifies the comparison process, as users can select sequences directly from the application. The program also serves as a DNA sequence trace editor, enabling the correction of base calls and cropping of low-quality areas. With options for marking regions and exporting sequences as PDF for publication, 4Peaks stands out as a robust tool for DNA analysis.