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For a number of conditions in dermatology, evidence-based diagnostic criteria have been developed to improve the diagnostic acuity. An accurate diagnosis is essential for proper patient management. This resource was created to meet the needs of residents, medical students, practicing physicians and researchers for an easy to use, quick reference with diagnostic criteria of diseases and syndromes in dermatology. The lists of criteria provided in this reference should not only aid in making an appropriate diagnosis, but on occasion, may also serve as a reminder of non-cutaneous involvement and the need for assessment of other organ systems.