From TOLIS Group:
BRU LE provides backup and restore for Mac systems. SCSI, SAS, Fibre-Channel, Firewire, and USB tape drives (single drive) and autoloaders (up to 10 slots) are fully supported. Additionally, disk-based files may be created allowing the use of removable MO or disk drives. BRU LE for Mac OS X is based upon our BRU 17.0 I/O engine (available in the Unix world since 1985) and includes all of the features of the command line BRU product available on Unix systems. BRU LE is fully 64 bit compatible (since 1992) and supports single file sizes greater than 2GB and filesystems and single archives up to 16 exabytes. Supports all OS X file types, including CFM/PEF and Mach-O binaries, Resource forks, Finder Info, and case-sensitive filenames under the HFS+ filesystems. Backup and restore of all Unix permissions. Supports archives that exceed one terabyte (1TB) and do not have a limit on the size of catalog that can be created. Properly accesses and processes filesystems larger than 1TB. Not dependent upon disk-based information, such as "save sets", for restores. Supports full backup of live systems. Provides "Smart Restore" which allows you to restore a backup to a live system without crashing the system. Automatically verifies backups using AUTOSCAN Verify - an out-of-band verification process that allows reduced backup window requirements. In addition to the graphical application, all of the command line and scripting functionality is still included at no additional cost.
This review was originally posted on VersionTracker.com. I've been using v1.2.8 for a couple of weeks now with an Exabyte Magnum 1x7 LTO-3 tape library to back up an Xserve and Xserve RAID. It was not as intuitive as I had hoped, but phone support has been excellent. They walked me through some minor issues that I had trouble with and the software runs great. There are some features that I'd like to see included in future updates or upgrades though.
For Mac users, I would recommend this software if your need requires control of a tape library device or even a stand-alone tape drive. For bootable drive backups, I use Super Duper! and am very pleased with that as well.