DiskMagik

From Rose City Software:

DiskMagik is an intelligently designed utility to defragment the hard drive of a Windows PC. DiskMagik has several powerful features not included in the Windows defrag utility including the ability to rearrange and re-prioritize the order of files on the disk, including the Windows Pagefile, permitting faster file access on demand. In addition, it includes optional Boot-time defrag and our exclusive "Proactive Defragmentation" technology. This extraordinary feature gives you the option to run DiskMagik silently in the background at all times. A MUST-HAVE for all computer users interested in maintaining their computer's performance to help keep your system in peak operating condition. Do not confuse DiskMagik and the performance enhancement it provides with registry optimizers. The Windows registry is an important component of Windows performance, but optimizing your registry does absolutely nothing about optimizing your computer's hard drive. The hard disk drive on a Windows PC is by far the slowest component on your PC. Even high amounts of memory (RAM) and a fast processor cannot overcome the limitations of a slow disk drive and nothing slows a hard drive down like excessive fragmentation. Although DiskMagik is a powerful tool suitable for advanced users, it is also perfect for the novice as well. A very user friendly multi step configuration wizard makes the initial setup a snap. Use DiskMagik with full confidence to enhance your computer's performance and keep your system in peak operating condition.

Version 3.6 works faster and includes better Vista and Windows 7 support.