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Developer's Description

QuasiRecomb is a lightweight application that runs in the command console, simulating a Markov model for generating viral Quasispecies. It describes the generation of the viral quasispecies and a method to infer its parameters by analysing next generation sequencing data. The model is validated on simulated data, showing the advantage of explicitly taking the recombination process into account, and tested by applying to reads obtained from experimental HIV samples. It offers an implementation of the EM algorithm to find maximum a posteriori estimates of the model parameters and a method to estimate the distribution of viral strains in the quasispecies.

Full Specifications

What's new in version 1.0

General

Release May 6, 2013
Date Added May 6, 2013
Version 1.0

Operating Systems

Operating Systems Windows 2003, Windows 2000, Windows Vista, Windows, Windows 7, Windows XP
Additional Requirements Java

Popularity

Total Downloads 30
Downloads Last Week 0
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