Virtual CloneDrive
Very good
Full user review
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"I use this all the time and it's great"
Pros
When installing a program from an ISO, you don't need to reboot off your CD/DVD drive to install apps like Windows 7 or anything that comes on CD. You'll need to know how to create an ISO from the files on your disk to do this, but once you have that done, you can install this program with ease using Virtual Clonedrive.
It's also free, so why NOT use it?Cons
None. I can't think of anything I don't like about it.