Trend Micro HijackThis
A newer version of Trend Micro HijackThis is available.
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Full user review
"Great program for intermediate to advanced users....."
This program is a great tool for anyone seeking to find any potential flaws in their system that could lead to spyware. The information provided is thorough enough that anyone with more than a beginner's knowledge should be able to effectively operate the program.
Can be a little over-aggressive with it's findings, and since it does not look for spyware instead searching for potential security flaws it may possibly list vital system folders as deletable files. Delete with caution.