From PortableApps: SpeedyFox optimizes the SQlite databases that many applications use to store their settings, bookmarks, history, and other data. It works with Mozilla Firefox, Mozilla Thunderbird, Skype, Google Chrome, and SRWare Iron. It will list and pre-select to optimize all the local applications it finds. It will automatically detect and set itself to optimize Mozilla Firefox, Portable Edition (stable, ESR and Test), Mozilla Thunderbird, Portable Edition (stable, ESR and Test), Google Chrome Portable (Stable, Beta and Dev), and Iron Portable.
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