From Special K Software:
Image In Focus software combines various out of focus images to create a single Montage composite in-focus images. Various microscope or digital camera images, each taken with a different focal plane can be combined (or stacked) into one perfectly in-focus picture. Each image, with a different portion in focus, is used to perfect the focus for the composite in-focus image. Sophisticated algorithms are used to make the best focus image possible. You can save, edit or directly print the image that you have created.
No new hardware is needed, as this software combines images you have already taken with your existing equipment. It is compatible with all cameras and optical and digital microscopes which can create digital image files. All features are user controllable, so that you get the maximum enhancement with a wide variety of different images. In 'auto' mode, these features are automatically optimized. This is why Image In Focus is recognized as the best value available.