EditSeq for Mac

From DNASTAR:

EditSeq enables you to work on nucleic acid and protein sequences of all sizes from a wide variety of popular formats. You can also utilize the integrated internet interface to search NCBI's databases to locate sequences by accession number, sequence similarity via BLAST, or keyword searches via the Entrez text query. For your convenience, EditSeq separates the sequence, comments and annotations into three editable panes. Dynamic links between the sequence and its annotations automatically update feature coordinates when you edit a sequence and provide feature inclusion when copying/pasting sequences. Available functionality also includes the ability to reverse complement, translate, back-translate sequences and identify ORFs. As with other Lasergene applications, EditSeq will handle sequences ranging in size from a couple of nucleotides to a whole bacterial genome.