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Full user review
"Best email client, and free to boot"
I use Thunderbird to manage 10 different email accounts that handle a lot of email and I've experienced almost no problems wince I've been using the program. I used to use Outlook 2000 and Outlook 2003, but after regular crashes lost tons of email repeatedly (grr), I made the switch and haven't looked back.
Other great things about Thunderbird: it's free and there are a lot of great plug ins available to do just about anything you could need.
Older versions seemed a little unstable, but the program keeps getting better and better (220.127.116.11 is out now).