PortableApps Suite (Standard Edition)
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Full user review
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"This is a must have utility"
Pros
Several very useful apps are included in the suite and many more available from portableapps.com and download.com. There are even tools on potable apps to make some of your other favorite programs portable.
Cons
Most programs that you buy don't have portable versions that you can plugin so you have to settle for freeware equivalents. Then again you might be able to use AppCompactor to make some of your favorite programs portable.
Summary
As a web designer I can carry all the tools I need to create websites there's even a portable Apache web server available in the form of XAMPP. I also have portable versions of KompoZer, Gimp, 7zip, PuTTY, FileZilla, and Firefox installed installed. Essentially everything you need to design most any website and I can carry it all on my thumbdrive. Hopefully someday soon there will be a Flash editor.
I have another Drive that I use for fixing other peoples computers. With Toucan backup, ClamWin Antivirus, Command Prompt, Eraser,and WinDirStat. I can fix most problems right from my thumbdrive.
I cant praise this software enough you have to download it and try it out for yourself.