Parkinson's

Google doodle honors eccentric photographer Norman Parkinson

It seems so obvious now, but taking pictures of models outside of a studio was something of a revolution in the 1940s and 50s.

For Norman Parkinson, the British photographer who would have been 100 years old today, it offered an opportunity for an additional elegance and simplicity.

"I never work in studios if I can help it, because working in a studio is such hard work," he told one interviewer.

A studio is merely an attempt to simulate daylight. Why not just plump for daylight in the first place?

Many think of Sir Norman (as he became) … Read more

Bots beat humans probing brain's neural activity

In what could be a major boon for the study of brain disorders such as schizophrenia, Parkinson's disease, autism, and epilepsy, researchers at MIT and Georgia Tech say they've figured out how to automate finding and recording information from neurons in live brains.

The process, described this week in the journal Nature Methods, involves a robotic arm guided by a cell-detecting algorithm that can identify and record data from neurons faster and more accurately than we mortal humans.

"In all [the abovementioned disorders], a molecular description of a cell that is integrated with [its] electrical and circuit … Read more

Parkinson's patients test video games as therapy (video)

An estimated 1.5 million Americans have Parkinson's disease, which causes slowness of movement, tremors, and loss of balance. Physical therapy can ease symptoms and may delay progression of the disease. Now, cutting-edge tech is transforming everyday therapy into entertaining exercises.

Parkinson's patients recently took part in a University of California at San Francisco study to see if special video games could replace their regular exercises. Scientific researchers and game developers came together to create the therapeutic games. Check out this SmartPlanet video that explores the technology.

This video originally appeared on SmartPlanet with the headline "Video games replace physical therapy for Parkinson's patients.&… Read more

Nifty stem-cell engineering sheds light on Parkinson's disease

Researchers at the University at Buffalo may have taken a significant step toward unraveling the way Parkinson's disease assails the human nervous system--thanks in part to a nifty bit of stem-cell engineering.

Scientists led by physiologist Jian Feng took skin cells from healthy control subjects and people with a particular type of Parkinson's disease and transformed them into a type of primordial cell--technically, an "induced pluripotent stem cell." Such iPS cells, as they're known, can be coaxed into developing as almost any type of cell in the body.

Here, they turned into brain cells. … Read more

The 404 927: Where a funny thing happened on the way to work today (podcast)

It's easy to get lost in all the new Android and Windows Phone handsets coming out soon, but CNET's Kent German, Bonnie Cha, and Nicole Lee have us covered. Today Verizon and Motorola announced their latest Droid Razr, a modern incarnation of the original Razr design with a non-bulletproof Kevlar backing and an ultraslim profile.

We also have a leaked shot of the Google Nexus Prime, a first take of the HTC Titan, and a Microsoft patent that encourages you to access touch screens through your pants. Too easy! This and more irreverent stories on today's episode of The 404 Podcast.… Read more

Brain 'pacemaker': Smarter Parkinson's care?

The idea of an electronic device implanted in the brain tends to evoke spooky scenarios a la "Total Recall." But if a team of international scientists has its way, brain implants will one day be viewed as a viable and commonplace therapy for conditions like Parkinson's disease, depression, and even age-related loss of brain elasticity.

The scientists are working on a biomimetic chip called the Rehabilitation Nano Chip (ReNaChip) that could be used to wire computer applications and sensors to the brain, building off of current procedures to make those approaches more precise.

The chip itself wouldn't be implanted in the brain; instead, it would be hooked up to tiny electrodes that provide precisely controlled stimulation to diseased areas.

An existing procedure called deep brain stimulation (DBS) is already used to treat neurological symptoms, most commonly Parkinson's effects such as tremor, rigidity, stiffness, slowed movement, and walking problems.

It involves a surgically implanted, battery-operated medical device called a neurostimulator that delivers electrical stimulation to targeted areas in the brain that control movement, blocking the abnormal nerve signals that cause Parkinson's symptoms.

However, the ReNaChip team says over-stimulation of the brain is a serious concern in current procedures, as it can cause patients to lose some therapeutic benefits over time. That's where their work comes in. … Read more

World's smallest neurostimulator gets green light

A 67-year-old man who has suffered from Parkinson's disease since his early 40s has become the first person in the world to be implanted with the Brio neurostimulator, which St. Jude Medical says has just earned CE Mark approval (CE stands for Conformite Europeenne).

Weighing in at just 1 ounce and measuring a mere 10 millimeters thick, the Brio is the smallest, longest-lasting rechargeable deep brain stimulator (DBS) that aims to treat the symptoms of Parkinson's in the world, according to its creator. One battery is supposed to survive a decade of recharging.

"Deep brain stimulation therapy … Read more

Sergey Brin starts blog, tells of Parkinson's risk

Google co-founder Sergey Brin launched his personal blog on Thursday with some sobering news: he carries a particular genetic mutation that means he's much more likely than average to get Parkinson's disease.

The inaugural post on Brin's blog, too.blogspot.com, is titled "LRRK2" after the gene that he found carries a mutation called G2019S, which, "while rare even among people with the disease, accounts, in some ethnic groups, for a substantial proportion of familial Parkinson's," Brin said in the blog post.

"It is clear that I have a markedly higher … Read more