McAfee's 2010 update to its consumer security suite line debuts a new vertical interface. There's a lot to like about it, most noticeably being the smooth organization of features. Some things should be tweaked, though, including the inability to resize the window and an easier way to return to your previous pane.
The version depicted here is the top-of-the-line McAfee Total Protection. The difference between it and McAfee Internet Security or McAfee AntiVirus Plus is that they have fewer features. The overall look, however, is the same.